The John Templeton Foundation serves as a philanthropic catalyst for discoveries relating to the Big Questions of human purpose and ultimate reality. It supports research on subjects ranging from complexity, evolution, and infinity to creativity, forgiveness, love, and free will. It encourages civil, informed dialogue among scientists, philosophers, and theologians and between such experts and the public at large, for the purposes of definitional clarity and new insights. Its vision is derived from the late Sir John Templeton’s optimism about the possibility of acquiring “new spiritual information” and from his commitment to rigorous scientific research and related scholarship. The foundation’s motto, “How little we know, how eager to learn,” exemplifies its support for open-minded inquiry and its hope for advancing human progress through breakthrough discoveries.